A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes

The transcriptional shift from repression to activation of target genes is crucial for the fidelity of Notch responses through incompletely understood mechanisms that likely involve chromatin-based control. To activate silenced genes, repressive chromatin marks are removed and active marks must be a...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Oswald, Franz, Rodriguez, Patrick, Giaimo, Benedetto Daniele, Antonello, Zeus A., Mira, Laura, Mittler, Gerhard, Thiel, Verena N., Collins, Kelly J., Tabaja, Nassif, Cizelsky, Wiebke, Rothe, Melanie, Kühl, Susanne J., Kühl, Michael, Ferrante, Francesca, Hein, Kerstin, Kovall, Rhett A., Dominguez, Maria, Borggrefe, Tilman
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Gene regulation, Chromatin and Epigenetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889922/
https://ncbi.nlm.nih.gov/pubmed/26912830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw105
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