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Enhancing protein stability with extended disulfide bonds

Disulfide bonds play an important role in protein folding and stability. However, the cross-linking of sites within proteins by cysteine disulfides has significant distance and dihedral angle constraints. Here we report the genetic encoding of noncanonical amino acids containing long side-chain thio...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Liu, Tao, Wang, Yan, Luo, Xiaozhou, Li, Jack, Reed, Sean A., Xiao, Han, Young, Travis S., Schultz, Peter G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889405/
https://ncbi.nlm.nih.gov/pubmed/27162342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605363113
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