Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor

The haptoglobin-haemoglobin receptor of the African trypanosome species, Trypanosoma brucei, is expressed when the parasite is in the bloodstream of the mammalian host, allowing it to acquire haem through the uptake of haptoglobin-haemoglobin complexes. Here we show that in Trypanosoma congolense th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Lane-Serff, Harriet, MacGregor, Paula, Peacock, Lori, Macleod, Olivia JS, Kay, Christopher, Gibson, Wendy, Higgins, Matthew K, Carrington, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2016
Pynciau:
Genomics and Evolutionary Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889325/
https://ncbi.nlm.nih.gov/pubmed/27083048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13044
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