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A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies

Persistent pathogens have evolved to avoid elimination by the mammalian immune system including mechanisms to evade complement. Infections with African trypanosomes can persist for years and cause human and animal disease throughout sub-Saharan Africa. It is not known how trypanosomes limit the acti...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Macleod, Olivia J. S., Bart, Jean-Mathieu, MacGregor, Paula, Peacock, Lori, Savill, Nicholas J., Hester, Svenja, Ravel, Sophie, Sunter, Jack D., Trevor, Camilla, Rust, Steven, Vaughan, Tristan J., Minter, Ralph, Mohammed, Shabaz, Gibson, Wendy, Taylor, Martin C., Higgins, Matthew K., Carrington, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067766/
https://ncbi.nlm.nih.gov/pubmed/32165615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15125-y
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