A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies

Persistent pathogens have evolved to avoid elimination by the mammalian immune system including mechanisms to evade complement. Infections with African trypanosomes can persist for years and cause human and animal disease throughout sub-Saharan Africa. It is not known how trypanosomes limit the acti...

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Publicat a:Nat Commun
Autors principals: Macleod, Olivia J. S., Bart, Jean-Mathieu, MacGregor, Paula, Peacock, Lori, Savill, Nicholas J., Hester, Svenja, Ravel, Sophie, Sunter, Jack D., Trevor, Camilla, Rust, Steven, Vaughan, Tristan J., Minter, Ralph, Mohammed, Shabaz, Gibson, Wendy, Taylor, Martin C., Higgins, Matthew K., Carrington, Mark
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7067766/
https://ncbi.nlm.nih.gov/pubmed/32165615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15125-y
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