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Mechanism of increased clearance of glycated albumin by proximal tubule cells

Serum albumin is the most abundant plasma protein and has a long half-life due to neonatal Fc receptor (FcRn)-mediated transcytosis by many cell types, including proximal tubule cells of the kidney. Albumin also interacts with, and is modified by, many small and large molecules. Therefore, the focus...

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Veröffentlicht in:Am J Physiol Renal Physiol
Hauptverfasser: Wagner, Mark C., Myslinski, Jered, Pratap, Shiv, Flores, Brittany, Rhodes, George, Campos-Bilderback, Silvia B., Sandoval, Ruben M., Kumar, Sudhanshu, Patel, Monika, Ashish, Molitoris, Bruce A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889321/
https://ncbi.nlm.nih.gov/pubmed/26887834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00605.2015
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