Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine

Recombinant immunotoxins (RITs) are chimeric proteins composed of an Fv and a protein toxin being developed for cancer treatment. The Fv brings the toxin to the cancer cell, but most of the RITs do not reach the tumor and are removed by other organs. To identify cells responsible for RIT removal, an...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Liu, Xui-Fen, Wei, Junxia, Zhou, Qi, Molitoris, Bruce A., Sandoval, Ruben, Kobayashi, Hisataka, Okada, Ryuhei, Nagaya, Tadanobu, Karim, Baktiar, Butcher, Donna, Pastan, Ira
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
Biological Sciences
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084118/
https://ncbi.nlm.nih.gov/pubmed/32123080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1919038117
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items