Загрузка...

Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding

Mesothelin is a cell-surface tumor-associated antigen expressed in several human cancers. The limited expression of mesothelin on normal tissues and its high expression in many cancers make it an attractive candidate for targeted therapies utilizing monoclonal antibodies, immunoconjugates and immuno...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Zhang, Yujian, Chertov, Oleg, Zhang, Jingli, Hassan, Raffit, Pastan, Ira
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165076/
https://ncbi.nlm.nih.gov/pubmed/21775520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0466
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!