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Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors
Recombinant immunotoxins are chimeric proteins composed of the Fv portion of a tumor-specific antibody fused to a toxin. SS1P (CAT-5001) is an immunotoxin composed of an antimesothelin Fv fused to a 38-kDa portion of Pseudomonas exotoxin A. Immunotoxins have been shown to be active in lymphomas and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040446/ https://ncbi.nlm.nih.gov/pubmed/17940013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708101104 |
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