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Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat

AIM: We have previously found that chronic endothelin-1 (ET-1) infusion in Sprague-Dawley rats increases glomerular permeability to albumin (P(alb)) as assessed in vitro independent of blood pressure with no observed albuminuria. In this study, we hypothesized that ET-1 increases glomerular albumin...

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Autors principals: Saleh, Mohamed A., Sandoval, Ruben M., Rhodes, George J., Campos-Bilderback, Silvia B., Molitoris, Bruce A., Pollock, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728660/
https://ncbi.nlm.nih.gov/pubmed/22727794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.007
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