Free radical scavenging decreases endothelin‐1 excretion and glomerular albumin permeability during type 1 diabetes

Increased renal endothelin‐1 (ET‐1) production and an ET(A) receptor‐dependent increase in glomerular albumin permeability (P(alb)) accompany type 1 diabetes mellitus (T1D). We hypothesized that T1D‐induced oxidative stress contributes to renal ET‐1 production and glomerular P(alb). Male rats with s...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Saleh, Mohamed A., De Miguel, Carmen, Stevens, David I., Carmines, Pamela K., Pollock, David M., Pollock, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210388/
https://ncbi.nlm.nih.gov/pubmed/28039404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13055
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