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Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts
Nephrogenic diabetes insipidus (NDI) is characterized by production of very large quantities of dilute urine due to an inability of the kidney to respond to vasopressin. Congenital NDI results from mutations in the type 2 vasopressin receptor (V(2)R) in ∼90% of families. These patients do not have m...
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| Pubblicato in: | Am J Physiol Renal Physiol |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889320/ https://ncbi.nlm.nih.gov/pubmed/26962099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00102.2016 |
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