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Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts
Nephrogenic diabetes insipidus (NDI) is characterized by production of very large quantities of dilute urine due to an inability of the kidney to respond to vasopressin. Congenital NDI results from mutations in the type 2 vasopressin receptor (V(2)R) in ∼90% of families. These patients do not have m...
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| Izdano u: | Am J Physiol Renal Physiol |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889320/ https://ncbi.nlm.nih.gov/pubmed/26962099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00102.2016 |
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