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Metformin, an AMPK activator, stimulates the phosphorylation of aquaporin 2 and urea transporter A1 in inner medullary collecting ducts

Nephrogenic diabetes insipidus (NDI) is characterized by production of very large quantities of dilute urine due to an inability of the kidney to respond to vasopressin. Congenital NDI results from mutations in the type 2 vasopressin receptor (V(2)R) in ∼90% of families. These patients do not have m...

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Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Renal Physiol
Egile Nagusiak: Klein, Janet D., Wang, Yanhua, Blount, Mitsi A., Molina, Patrick A., LaRocque, Lauren M., Ruiz, Joseph A., Sands, Jeff M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889320/
https://ncbi.nlm.nih.gov/pubmed/26962099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00102.2016
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