Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling

Calorie restriction (CR) extends lifespan from yeast to mammals. SIRT6 is a member of the sirtuin family of NAD(+)-dependent histone deacetylases, which is responsible for mediating the effects of CR. The transcription factor NF-κB, which is involved in inflammation and aging, has been shown to be r...

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Publicat a:Cell Cycle
Autors principals: Zhang, Nannan, Li, Zhongchi, Mu, Wei, Li, Liyuan, Liang, Yaru, Lu, Maoyang, Wang, Zhuoran, Qiu, Ying, Wang, Zhao
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889297/
https://ncbi.nlm.nih.gov/pubmed/26940461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1152427
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