Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin

Cyclic adenosine monophosphate (cAMP) plays an important role in many biological processes as a second messenger, and cAMP treatment has been reported to extend the lifespan of wild-type Drosophila melanogaster. Our study showed that exogenous cAMP improved ageing-related phenotypes by increasing th...

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Udgivet i:Sci Rep
Main Authors: Wang, Zhuoran, Zhang, Lu, Liang, Yaru, Zhang, Chi, Xu, Zhiyu, Zhang, Lang, Fuji, Ryosuke, Mu, Wei, Li, Liyuan, Jiang, Junjun, Ju, Yong, Wang, Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4648391/
https://ncbi.nlm.nih.gov/pubmed/26153625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12012
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