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Metabolic and Neuropsychiatric Effects of Calorie Restriction and Sirtuins

Most living organisms, including humans, age. Over time the ability to do physical and intellectual work deteriorates, and susceptibility to infectious, metabolic, and neurodegenerative diseases increases, which leads to general fitness decline and ultimately to death. Work in model organisms has de...

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Bibliographic Details
Main Authors: Libert, Sergiy, Guarente, Lenny
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570673/
https://ncbi.nlm.nih.gov/pubmed/23043250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-physiol-030212-183800
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