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Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?

Recent studies of calorie restriction in several organisms demonstrate an increase in mitochondrial activity that is associated with the salutary effects of this dietary restriction regimen. In this Essay, I speculate on how an increase in mitochondrial activity might provide benefit and discuss how...

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Bibliographic Details
Main Author: Guarente, Leonard
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680180/
https://ncbi.nlm.nih.gov/pubmed/18243090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.01.007
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