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Calorie restriction-induced SIRT6 activation delays aging by suppressing NF-κB signaling
Calorie restriction (CR) extends lifespan from yeast to mammals. SIRT6 is a member of the sirtuin family of NAD(+)-dependent histone deacetylases, which is responsible for mediating the effects of CR. The transcription factor NF-κB, which is involved in inflammation and aging, has been shown to be r...
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| Pubblicato in: | Cell Cycle |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889297/ https://ncbi.nlm.nih.gov/pubmed/26940461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1152427 |
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