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Structure of the human dimeric ATM kinase
DNA-double strand breaks activate the serine/threonine protein kinase ataxia-telangiectasia mutated (ATM) to initiate DNA damage signal transduction. This activation process involves autophosphorylation and dissociation of inert ATM dimers into monomers that are catalytically active. Using single-pa...
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| Publicat a: | Cell Cycle |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889239/ https://ncbi.nlm.nih.gov/pubmed/27097373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1158362 |
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