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Aging is associated with hypermethylation of autophagy genes in macrophages

Autophagy is a biological process characterized by self-digestion and involves induction of autophagosome formation, leading to degradation of autophagic cargo. Aging is associated with the reduction of autophagy activity leading to neurodegenerative disorders, chronic inflammation, and susceptibili...

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Bibliographic Details
Published in:Epigenetics
Main Authors: Khalil, Hany, Tazi, Mia, Caution, Kyle, Ahmed, Amr, Kanneganti, Apurva, Assani, Kaivon, Kopp, Benjamin, Marsh, Clay, Dakhlallah, Duaa, Amer, Amal O.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889231/
https://ncbi.nlm.nih.gov/pubmed/26909551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1144007
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