Elevated Mirc1/Mir17-92 cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages

Cystic fibrosis (CF) is a fatal, genetic disorder that critically affects the lungs and is directly caused by mutations in the CF transmembrane conductance regulator (CFTR) gene, resulting in defective CFTR function. Macroautophagy/autophagy is a highly regulated biological process that provides ene...

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Bibliografske podrobnosti
izdano v:Autophagy
Main Authors: Tazi, Mia F., Dakhlallah, Duaa A., Caution, Kyle, Gerber, Madelyn M., Chang, Sheng-Wei, Khalil, Hany, Kopp, Benjamin T., Ahmed, Amr E., Krause, Kathrin, Davis, Ian, Marsh, Clay, Lovett-Racke, Amy E., Schlesinger, Larry S., Cormet-Boyaka, Estelle, Amer, Amal O.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Basic Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103351/
https://ncbi.nlm.nih.gov/pubmed/27541364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1217370
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