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The many faces of histone H3K79 methylation

Dot1/DOT1L (disruptor of telomeric silencing-1) is an evolutionarily conserved histone methyltransferase that methylates lysine 79 located within the globular domain of histone H3. Dot1 was initially identified by a genetic screen as a disruptor of telomeric silencing in Saccharomyces cerevisiae; fu...

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Detalhes bibliográficos
Publicado no:Mutat Res Rev Mutat Res
Main Authors: Farooq, Zeenat, Banday, Shahid, Pandita, Tej K., Altaf, Mohammad
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889126/
https://ncbi.nlm.nih.gov/pubmed/27234562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrrev.2016.03.005
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