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Therapeutic strategies against hDOT1L as a potential drug target in MLL-rearranged leukemias
Therapeutic intervention of proteins participating in chromatin-mediated signaling with small-molecules is a novel option to reprogram expression networks for restraining disease states. Protein methyltransferases form the prominent family of such proteins regulating gene expression via epigenetic m...
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| Pubblicato in: | Clin Epigenetics |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7249331/ https://ncbi.nlm.nih.gov/pubmed/32450905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00860-2 |
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