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The diverse functions of Dot1 and H3K79 methylation

DOT1 (disruptor of telomeric silencing; also called Kmt4) was initially discovered in budding yeast in a genetic screen for genes whose deletion confers defects in telomeric silencing. Since the discovery ∼10 years ago that Dot1 and its mammalian homolog, DOT1L (DOT1-Like), possess histone methyltra...

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Detalhes bibliográficos
Main Authors: Nguyen, Anh Tram, Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3134078/
https://ncbi.nlm.nih.gov/pubmed/21724828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2057811
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