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The diverse functions of Dot1 and H3K79 methylation
DOT1 (disruptor of telomeric silencing; also called Kmt4) was initially discovered in budding yeast in a genetic screen for genes whose deletion confers defects in telomeric silencing. Since the discovery ∼10 years ago that Dot1 and its mammalian homolog, DOT1L (DOT1-Like), possess histone methyltra...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3134078/ https://ncbi.nlm.nih.gov/pubmed/21724828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2057811 |
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