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Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation

INTRODUCTION: Nucleosomes—the primary, repeating unit of chromatin—package and protect the genome while also transmitting various regulatory signals through, in part, posttranslational modifications of histones. These histone modifications (for example, acetylation, ubiquitination, or methylation) a...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Valencia-Sánchez, Marco Igor, De Ioannes, Pablo, Wang, Miao, Truong, David M., Lee, Rachel, Armache, Jean-Paul, Boeke, Jef D., Armache, Karim-Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279004/
https://ncbi.nlm.nih.gov/pubmed/33479126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc6663
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