Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation

INTRODUCTION: Nucleosomes—the primary, repeating unit of chromatin—package and protect the genome while also transmitting various regulatory signals through, in part, posttranslational modifications of histones. These histone modifications (for example, acetylation, ubiquitination, or methylation) a...

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Bibliografiska uppgifter
I publikationen:Science
Huvudupphovsmän: Valencia-Sánchez, Marco Igor, De Ioannes, Pablo, Wang, Miao, Truong, David M., Lee, Rachel, Armache, Jean-Paul, Boeke, Jef D., Armache, Karim-Jean
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8279004/
https://ncbi.nlm.nih.gov/pubmed/33479126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abc6663
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