APOBEC4 Enhances the Replication of HIV-1

APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic expression of A4 in HeLa cells resulted in mostly...

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Udgivet i:PLoS One
Main Authors: Marino, Daniela, Perković, Mario, Hain, Anika, Jaguva Vasudevan, Ananda A., Hofmann, Henning, Hanschmann, Kay-Martin, Mühlebach, Michael D., Schumann, Gerald G., König, Renate, Cichutek, Klaus, Häussinger, Dieter, Münk, Carsten
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889046/
https://ncbi.nlm.nih.gov/pubmed/27249646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155422
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