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Model structure of APOBEC3C reveals a binding pocket modulating ribonucleic acid interaction required for encapsidation
Human APOBEC3 (A3) proteins form part of the intrinsic immunity to retroviruses. Carrying 1 or 2 copies of a cytidine deaminase motif, A3s act by deamination of retroviral genomes during reverse transcription. HIV-1 overcomes this inhibition by the Vif protein, which prevents incorporation of A3 int...
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| Main Authors: | , , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2009
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715496/ https://ncbi.nlm.nih.gov/pubmed/19581596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900979106 |
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