APOBEC4 Enhances the Replication of HIV-1

APOBEC4 (A4) is a member of the AID/APOBEC family of cytidine deaminases. In this study we found a high mRNA expression of A4 in human testis. In contrast, there were only low levels of A4 mRNA detectable in 293T, HeLa, Jurkat or A3.01 cells. Ectopic expression of A4 in HeLa cells resulted in mostly...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Marino, Daniela, Perković, Mario, Hain, Anika, Jaguva Vasudevan, Ananda A., Hofmann, Henning, Hanschmann, Kay-Martin, Mühlebach, Michael D., Schumann, Gerald G., König, Renate, Cichutek, Klaus, Häussinger, Dieter, Münk, Carsten
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889046/
https://ncbi.nlm.nih.gov/pubmed/27249646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0155422
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