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Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

E2/nonstructural protein 1, the putative envelope glycoprotein (gp72) of HCV, possesses an N-terminal hypervariable (E2 HV) domain from amino acids 384 to 414 of unknown significance. The high degree of amino acid sequence variation in the E2 HV domain appears to be comparable to that observed in th...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Weiner, A J, Geysen, H M, Christopherson, C, Hall, J E, Mason, T J, Saracco, G, Bonino, F, Crawford, K, Marion, C D, Crawford, K A
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1992
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3468
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