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Production of site-selected neutralizing human monoclonal antibodies against the third variable domain of the human immunodeficiency virus type 1 envelope glycoprotein.

Cell lines secreting IgG1 human monoclonal antibodies (mAb) to the envelope glycoprotein, gp120, of human immunodeficiency virus (HIV) have been produced by transformation of peripheral blood cells from HIV-infected individuals and by fusion of transformed cells to a human-mouse heteromyeloma cell l...

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Bibliographic Details
Main Authors: Gorny, M K, Xu, J Y, Gianakakos, V, Karwowska, S, Williams, C, Sheppard, H W, Hanson, C V, Zolla-Pazner, S
Format: Artigo
Language:Inglês
Published: 1991
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51421/
https://ncbi.nlm.nih.gov/pubmed/2014246
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