Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

E2/nonstructural protein 1, the putative envelope glycoprotein (gp72) of HCV, possesses an N-terminal hypervariable (E2 HV) domain from amino acids 384 to 414 of unknown significance. The high degree of amino acid sequence variation in the E2 HV domain appears to be comparable to that observed in th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Weiner, A J, Geysen, H M, Christopherson, C, Hall, J E, Mason, T J, Saracco, G, Bonino, F, Crawford, K, Marion, C D, Crawford, K A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3468
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