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Evidence for immune selection of hepatitis C virus (HCV) putative envelope glycoprotein variants: potential role in chronic HCV infections.

E2/nonstructural protein 1, the putative envelope glycoprotein (gp72) of HCV, possesses an N-terminal hypervariable (E2 HV) domain from amino acids 384 to 414 of unknown significance. The high degree of amino acid sequence variation in the E2 HV domain appears to be comparable to that observed in th...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: Weiner, A J, Geysen, H M, Christopherson, C, Hall, J E, Mason, T J, Saracco, G, Bonino, F, Crawford, K, Marion, C D, Crawford, K A
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1992
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48889/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1314389/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.8.3468
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