Production, Purification, and Characterization of (15)N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements

Oxidatively induced DNA damage is caused in living organisms by a variety of damaging agents, resulting in the formation of a multiplicity of lesions, which are mutagenic and cytotoxic. Unless repaired by DNA repair mechanisms before DNA replication, DNA lesions can lead to genomic instability, whic...

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Détails bibliographiques
Publié dans:Methods Enzymol
Auteurs principaux: Reddy, Prasad T., Jaruga, Pawel, Nelson, Bryant C., Lowenthal, Mark S., Jemth, Ann-Sofie, Loseva, Olga, Coskun, Erdem, Helleday, Thomas, Dizdaroglu, Miral
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888786/
https://ncbi.nlm.nih.gov/pubmed/26791985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2015.06.044
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