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Brain transplants of cells expressing the carboxyl-terminal fragment of the Alzheimer amyloid protein precursor cause specific neuropathology in vivo.

PC12 cells transfected with retroviral recombinants expressing the carboxyl-terminal 104 amino acids of the Alzheimer amyloid protein precursor (beta APP-C104) or PC12 cells transfected with the retroviral vector (DO) alone were transplanted into the brains of newborn mice. At 20 days after grafting...

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Bibliografiska uppgifter
Huvudupphovsmän: Neve, R L, Kammesheidt, A, Hohmann, C F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC48885/
https://ncbi.nlm.nih.gov/pubmed/1565637
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