Llwytho...

Major Carboxyl terminal fragments generated by Gamma-secretase processing of the Alzheimer’s amyloid precursor are 50 and 51 aa in length

OBJECTIVES: To understand the cleavage of the amyloid β protein (Aβ) precursor by γ-secretase and determine its changes in a representative Familial (FAD) Alzheimer’s disease (AD) mutation. METHODS: Transfected cells expressing wild type and FAD mutant APP were analyzed for changes in the levels of...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pinnix, Inga, Ghiso, Jorge A., Pappolla, Miguel A., Sambamurti, Kumar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740189/
https://ncbi.nlm.nih.gov/pubmed/23570890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jagp.2013.02.009
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