Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease

INTRODUCTION: Inhibition of gamma-secretase presents a direct target for lowering Aβ production in the brain as a therapy for Alzheimer's disease (AD). However, gamma-secretase is known to process multiple substrates in addition to amyloid precursor protein (APP), most notably Notch, which has...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Basi, Guriqbal S, Hemphill, Susanna, Brigham, Elizabeth F, Liao, Anna, Aubele, Danielle L, Baker, Jeanne, Barbour, Robin, Bova, Michael, Chen, Xiao-Hua, Dappen, Michael S, Eichenbaum, Tovah, Goldbach, Erich, Hawkinson, Jon, Lawler-Herbold, Rose, Hu, Kang, Hui, Terence, Jagodzinski, Jacek J, Keim, Pamela S, Kholodenko, Dora, Latimer, Lee H, Lee, Mike, Marugg, Jennifer, Mattson, Matthew N, McCauley, Scott, Miller, James L, Motter, Ruth, Mutter, Linda, Neitzel, Martin L, Ni, Huifang, Nguyen, Lan, Quinn, Kevin, Ruslim, Lany, Semko, Christopher M, Shapiro, Paul, Smith, Jenifer, Soriano, Ferdie, Szoke, Balazs, Tanaka, Kevin, Tang, Pearl, Tucker, John A, Ye, Xiacong Michael, Yu, Mei, Wu, Jing, Xu, Ying-zi, Garofalo, Albert W, Sauer, John Michael, Konradi, Andrei W, Ness, Daniel, Shopp, George, Pleiss, Michael A, Freedman, Stephen B, Schenk, Dale
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031881/
https://ncbi.nlm.nih.gov/pubmed/21190552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt60
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller