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Reduction of cytosolic phospholipase A(2)α upregulation delays the onset of symptoms in SOD1G93A mouse model of amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal multifactorial neurodegenerative disease characterized by selective death of motor neurons in the cortex, brainstem, and spinal cord. Cytosolic phospholipase A(2) alpha (cPLA(2)α) upregulation and activation in the spinal cord of patients wi...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Solomonov, Yulia, Hadad, Nurit, Levy, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888471/
https://ncbi.nlm.nih.gov/pubmed/27250836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0602-y
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