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Light-induced nuclear export reveals rapid dynamics of epigenetic modifications
We engineered a photoactivatable system for rapidly and reversibly exporting proteins from the nucleus by embedding a nuclear export signal in the LOV2 domain from phototropin 1. Fusing the chromatin modifier Bre1 to the photoswitch, we achieved light-dependent control of histone H2B monoubiquitylat...
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| I publikationen: | Nat Chem Biol |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4888063/ https://ncbi.nlm.nih.gov/pubmed/27089030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2068 |
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