Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model

Lymphatic vasculature critically depends on the connections of lymphatic endothelial cells with the extracellular matrix (ECM), which are mediated by anchoring filaments (AFs). The ECM protein EMILIN1 is a component of AFs and is involved in the regulation of lymphatic vessel functions: accordingly,...

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Detalles Bibliográficos
Publicado en:Clin Sci (Lond)
Autores principales: Pivetta, Eliana, Wassermann, Bruna, Belluz, Lisa Del Bel, Danussi, Carla, Modica, Teresa Maria Elisa, Maiorani, Orlando, Bosisio, Giulia, Boccardo, Francesco, Canzonieri, Vincenzo, Colombatti, Alfonso, Spessotto, Paola
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2016
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Original Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888021/
https://ncbi.nlm.nih.gov/pubmed/26920215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20160064
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