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Local inhibition of elastase reduces EMILIN1 cleavage reactivating lymphatic vessel function in a mouse lymphoedema model

Lymphatic vasculature critically depends on the connections of lymphatic endothelial cells with the extracellular matrix (ECM), which are mediated by anchoring filaments (AFs). The ECM protein EMILIN1 is a component of AFs and is involved in the regulation of lymphatic vessel functions: accordingly,...

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Библиографические подробности
Опубликовано в: :Clin Sci (Lond)
Главные авторы: Pivetta, Eliana, Wassermann, Bruna, Belluz, Lisa Del Bel, Danussi, Carla, Modica, Teresa Maria Elisa, Maiorani, Orlando, Bosisio, Giulia, Boccardo, Francesco, Canzonieri, Vincenzo, Colombatti, Alfonso, Spessotto, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4888021/
https://ncbi.nlm.nih.gov/pubmed/26920215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20160064
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