EMILIN1–α4/α9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation

EMILIN1 promotes α4β1 integrin–dependent cell adhesion and migration and reduces pro–transforming growth factor–β processing. A knockout mouse model was used to unravel EMILIN1 functions in skin where the protein was abundantly expressed in the dermal stroma and where EMILIN1-positive fibrils reache...

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Bibliographic Details
Main Authors: Danussi, Carla, Petrucco, Alessandra, Wassermann, Bruna, Pivetta, Eliana, Modica, Teresa Maria Elisa, Belluz, Lisa Del Bel, Colombatti, Alfonso, Spessotto, Paola
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187715/
https://ncbi.nlm.nih.gov/pubmed/21949412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008013
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