Deposition of BACE-1 Protein in the Brains of APP/PS1 Double Transgenic Mice

The main causes of Alzheimer's disease remain elusive. Previous data have implicated the BACE-1 protein as a central player in the pathogenesis of Alzheimer's disease. However, many inhibitors of BACE-1 have failed during preclinical and clinical trials for AD treatment. Therefore, uncover...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Luo, Gang, Xu, Hongxia, Huang, Yinuo, Mo, Dapeng, Song, Ligang, Jia, Baixue, Wang, Bo, Jin, Zhanqiang, Miao, Zhongrong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887654/
https://ncbi.nlm.nih.gov/pubmed/27294139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8380618
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