Wird geladen...
Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer’s disease
Pathological features in Alzheimer’s brains include mitochondrial dysfunction and dystrophic neurites (DNs) in areas surrounding amyloid plaques. Using a mouse model that overexpresses reticulon 3 (RTN3) and spontaneously develops age-dependent hippocampal DNs, here we report that DNs contain both R...
Gespeichert in:
| Veröffentlicht in: | Mol Psychiatry |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887420/ https://ncbi.nlm.nih.gov/pubmed/26619807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.181 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|