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Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer’s disease
Pathological features in Alzheimer’s brains include mitochondrial dysfunction and dystrophic neurites (DNs) in areas surrounding amyloid plaques. Using a mouse model that overexpresses reticulon 3 (RTN3) and spontaneously develops age-dependent hippocampal DNs, here we report that DNs contain both R...
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| Publicado no: | Mol Psychiatry |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887420/ https://ncbi.nlm.nih.gov/pubmed/26619807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.181 |
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