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Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation
Activation of the inducible caspase 9 (iC9) safety gene by a dimerizing drug (chemical inducer of dimerization (CID) AP1903) effectively resolves the symptoms and signs of graft-versus-host disease (GvHD) in haploidentical stem cell transplant (HSCT) recipients. However, after CID treatment, 1% of i...
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| Publicado en: | Mol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886936/ https://ncbi.nlm.nih.gov/pubmed/26708005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.234 |
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