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Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch
Safety switches are becoming relevant for the clinical translation of T-cell–based immunotherapies. In patients receiving an allogeneic hematopoietic stem cell transplant, the inducible caspase-9 gene (iC9) safety switch expressed by donor-derived T lymphocytes efficiently controls acute graft versu...
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Publicado no: | Mol Ther |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4886929/ https://ncbi.nlm.nih.gov/pubmed/26639404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.217 |
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