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Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents. Cell migratory defects have been identified i...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Shim, Joon W., Sandlund, Johanna, Hameed, Mustafa Q., Blazer-Yost, Bonnie, Zhou, Feng C., Klagsbrun, Michael, Madsen, Joseph R.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886677/
https://ncbi.nlm.nih.gov/pubmed/27243144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26794
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