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Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus

Heparin binding epidermal growth factor-like growth factor (HB-EGF) is an angiogenic factor mediating radial migration of the developing forebrain, while vascular endothelial growth factor (VEGF) is known to influence rostral migratory stream in rodents. Cell migratory defects have been identified i...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Shim, Joon W., Sandlund, Johanna, Hameed, Mustafa Q., Blazer-Yost, Bonnie, Zhou, Feng C., Klagsbrun, Michael, Madsen, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886677/
https://ncbi.nlm.nih.gov/pubmed/27243144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26794
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